Abstract

A 97-yr-old, male, captive desert tortoise (Gopherus agassizii) had a 2-month history of lethargy. Imaging with ultrasound, radiographs, and computed tomography revealed a 10-cm-diameter mass in the caudal coelom. Fine-needle aspiration revealed spindle and epithelial cell proliferations with formation of rosettes. Exploratory surgery was performed and the mass was removed and submitted for pathology. There was no evidence of metastasis on imaging or at surgery. Histology revealed a mass arising from and compressing the kidney. The mass was composed of primitive glomeruli, tubules, blastemal cells, and mesenchymal cells, features that are diagnostic for nephroblastoma. Tubules were reactive to cytokeratin and mesenchymal cells were reactive to desmin via immunohistochemistry; other immunohistochemical markers were either negative (e.g., S-100) or noncontributory (e.g., epithelial membrane antigen, myogenin, vimentin, and Wilms' Tumor 1). This is the first report of nephroblastoma in a chelonian.

An 8-year-old freshwater common musk turtle (Sternotherus odoratus) presented with a solid, reddened, non-mobile mass on the right forelimb that was reported to develop one week prior to presentation. The 6 × 4 × 3.5 cm mass was surgically excised and found to have a thin membranous lining. Histopathology revealed a completely excised mass with some infiltrative growth and up to 18 mitotic figures in 10 high-power fields. Immunohistochemistry was used to confirm a diagnosis of rhabdomyosarcoma using the criteria developed for humans and dogs. This mass was not positive for α-smooth muscle actin, which supports the diagnosis

Infectious Diseases of Reptiles: Peer-Reviewed Publications, January–June 2021

Chemotherapy-Responsive Acute Myeloid Leukemia in a Veiled Chameleon (Chamaeleo calyptratus)

Ovarian Torsion with Resulting Constipation in a Panther Chameleon (Furcifer pardalis)

Transplastron Enterocentesis to Manage Buoyancy Disorder in an Adult Loggerhead Sea Turtle (Caretta caretta)

Cytologic and Histologic Findings of Nephroblastoma in a Captive Desert Tortoise (Gopherus agassizii)

Abstract

Detection of Ophidiomyces ophidiicola in a Wild Burmese Python (Python bivittatus) in Hong Kong SAR, China

Surgical Management of a Digestive Tract Hernia in a Wild Marsh Frog (Pelophylax ridibundus)

Coagulopathy Secondary to Chronic Hepatopathy in Three Lizards

Using a Commercial Gut Loading Diet to Create a Positive Calcium to Phosphorus Ratio in Mealworms (Tenebrio molitor)

Evaluation of Paromomycin Treatment for Cryptosporidium serpentis Infection in Eastern Indigo Snakes (Drymarchon couperi)

Cross-Matching the San Cristóbal Galápagos Tortoise (Chelonoidis chathamensis)

Capsule Reports

Ophidiomycosis Outbreak in Captive Green Anacondas (Eunectes murinus): Management and Therapeutic Trials

Measuring the Physiologic Effects of Tricaine Methanesulfonate Sedation in Juvenile Lemur Tree Frogs (Agalychnis lemur)

Development of a Standardized Coelomic Veterinary Point of Care Ultrasound (VPOCUS) Exam in Multiple Snake Species: Pilot Study

Impact of Commercial Diets on the Nutritional Value and Mortality Rates of Dubia Roaches (Blaptica dubia)

Use of Neuraxial Anesthesia for Tail Amputation in a Sedated Central Bearded Dragon (Pogona vitticeps)

Capsule Reports

A Unique Disease Presentation Associated with a Mesomycetozoean-Like Organism in the Jeweled Chameleon (Furcifer campani)

Cytologic and Histologic Findings of Nephroblastoma in a Captive Desert Tortoise (Gopherus agassizii)

In Memoriam for Professor Dr. Peernel (Peer) Zwart, DVM, PhD, Dipl ECVP

Preliminary Results of Variation in Plasma N-acetyl-beta-d-glucosaminidase Concentration among Bearded Dragons (Pogona vitticeps), Corn Snakes (Pantherophis guttatus), and Wood Turtles (Glyptemys insculpta)